Anti-p300 Rabbit Polyclonal Antibody

Anti-p300 Rabbit Polyclonal Antibody

Author: ApexBio

spu:

PA1260

shortsummary:

Anti-p300 Rabbit Polyclonal Antibody

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M.Wt:

Calculated MW: 264 kDa; Observed MW: 300 kDa

Storage:

-20°C

DeliveryTime:

Ship with 3-5 days

HDAC inhibitor

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Blue ice

description:

EP300: E1A binding protein p300. This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.

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APExBIO Technology LLC is a premier provider of Small Molecule Inhibitors/Activators, Compound Libraries, Peptides, Assay Kits, Fluorescent Labels, Enzymes, Modified Nucleotides, mRNA synthesis and various tools for Molecular Biology. We carry a broad product line in over 25503 different research areas such as cancer, immunology, neurosciences, apoptosis and epigenetics etc. Based in USA (Houston, Texas), we have been serving the needs of customers across the world.