KIN-59

KIN-59

Author: ApexBio

spu:

C4148

CAS:

4152-77-6

purity:

0.98

shortsummary:

thymidine phosphorylase (Tpase) inhibitor

buy 50264-69-2

Synonyms:

5’-O-Tritylinosine

Z-DEVD-FMK Formula

Formula:

C29H26N4O5

M.Wt:

510.5

Chemical Name:

5'-O-(triphenylmethyl)-inosine

SMILES:

O[C@H]1[C@@H](O)[C@H](N2C=NC3=C2N=CNC3=O)O[C@@H]1COC(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6

Solubility:

≤0.3mg/ml in ethanol;16mg/ml in DMSO;5mg/ml in dimethyl formamide

Storage:

Store at -20°C

Physical Appearance:

A crystalline solid

DeliveryTime:

Ship with 5-10 days

Protein kinase inhibitor, potent and cell permeable

ShippingType:

Blue ice

description:

KIN59, the purine riboside derivative, is a noncompetitive inhibitor against human and bacterial recombinant TPase [1]. TPase is an enzyme with an important role in the pyrimidine nucleoside salvage pathway and the inactivation of cytotoxic pyrimidine nucleoside analogues. TPase also recognizes several nucleoside analogues clinically used as antiviral or anti-tumor agents [1]. Overexpression of TPase has been observed in many solid tumors [1].

related websites:

APExBIO Technology LLC is a premier provider of Small Molecule Inhibitors/Activators, Compound Libraries, Peptides, Assay Kits, Fluorescent Labels, Enzymes, Modified Nucleotides, mRNA synthesis and various tools for Molecular Biology. We carry a broad product line in over 15951 different research areas such as cancer, immunology, neurosciences, apoptosis and epigenetics etc. Based in USA (Houston, Texas), we have been serving the needs of customers across the world.